Respiratory Medicine Journal

Long-term oxygen therapy (LTOT) for bronchiectasis is recommended using the same eligibility criteria as for chronic obstructive pulmonary disease (COPD); however, the evidence supporting LTOT in bronchiectasis is limited, and no studies have evaluated the prognosis of the disease in these patients. The aim of the present study was to investigate the characteristics and prognosis of bronchiectasis in patients receiving LTOT.

Oscillometry has gained attention as a respiratory function test that does not require patient effort, particularly in older individuals and in those with severe respiratory disease. Although spirometry is essential for classifying the severity of chronic obstructive pulmonary disease (COPD), it requires forced expiration, which may be difficult in frail patients. In COPD, the slope of the respiratory reactance curve measured by oscillometry changes. This study evaluated the usefulness of a novel index, [X5×(Fres−5)]/ALX, which quantifies the frequency dependence of respiratory reactance using parameters measurable by oscillometry.

Futier et al. recently reported the results of the IMPROVE-2 trial[1]. They found that individualized high-PEEP strategies targeting a driving pressure <13 cmH2O did not reduce postoperative respiratory failure or death. Instead, these strategies were associated with higher rates of reintubation and therapeutic non-invasive ventilation (NIV). These findings contrast with a recent randomized controlled trial (RCT) in hypoxemic respiratory failure, where higher PEEP during NIV reduced treatment failure without excess adverse events[2].

To quantify prescription of COPD maintenance treatment in patients hospitalised with an exacerbation.

To analyze the correlation between S100A8/A9, protein kinase B (AKT)/nuclear transcription factor κB (NF-κB) expression and the severity/prognosis of type 2 diabetes mellitus (T2DM) complicated with severe pneumonia, and provide a reference for improving clinical prognosis.

Pulmonary arterial hypertension (PAH) is a rare, progressive disease with significant morbidity and mortality. New medications have improved outcomes, but adherence is crucial.

People with CF (pwCF) have decreased lung function, lean body mass, tensile strength, and exercise tolerance compared to age-matched healthy individuals. We investigated the relationship between peripheral muscle strength, pulmonary function, and inspiratory muscle strength in pwCF.

Malignant central airway obstruction (MCAO) secondary to lung cancer can result in unilateral total lung atelectasis, a life-threatening condition with limited data on survival outcomes and the role of therapeutic bronchoscopy. This study aimed to evaluate survival and prognostic factors in lung cancer patients with MCAO-induced total lung atelectasis and to assess the impact of bronchoscopic interventions.

We aimed to figure out the risk factors for cardiovascular disease (CVD) in the participants with non-obese sleep disordered breathing (SDB).

Rigby, Mikis D. Stasinopoulous, Achim Zeilis, Sanja Stanojevic, Gillian Heller, Fernanda de Bastiani, Thomas Kneib, Andreas Mayr, Reto Stauffer, and Nikolaus Umlauf contend that segmented linear regression (SLR) is inadequate for spirometry reference equations and over/under-diagnoses abnormality compared with Generalized Additive Models of Location, Scale, and Shape (GAMLSS). Using a refined NHANES 2007-2012 dataset (n=16,596), I reassessed calibration and the lower limit of normal (LLN) discordance with additional analyses.