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Gastroenterology

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Clinical Knowledge Summaries- Gastrointestinal Topics

COVID-19 – PubMed search results

Influenza vaccine uptake among patients with inflammatory bowel disease: comparable outcomes between telemedicine and in-person care
CONCLUSIONS: IBD-specific Tele-M did not adversely affect influenza vaccine uptake among patients with IBD. These findings highlight the importance of ensuring vaccination compliance irrespective of healthcare delivery modes. Collaboration among healthcare providers is crucial to improve vaccination rates in patients with IBD.
Comparison of immunity-boosting regimens for COVID-19 upon initiation of immunosuppressive therapy (CIRCUIT): study protocol for a randomised, controlled clinical trial
INTRODUCTION: Immunosuppression is associated with an increased risk of delayed SARS-CoV-2 viral clearance, severe COVID-19 and related death. This heterogeneous group of affected patients includes but is not limited to those with a haematological malignancy, people on immunosuppressive therapy for the treatment of autoimmune/inflammatory diseases and those following bone marrow transplantation (BMT). Immunosuppression is associated with decreased rates of anti-spike IgG seroconversion following...
Prevalence of hepatitis B surface antibodies and hepatitis B exposure in Belgium: results from a nationwide population-based serosurvey
No abstract
Correlation Between Disease Severity and Chest Computed Tomography Findings in Coronavirus Disease 2019 Patients in a University Hospital of Bangladesh-An Observational Study
CONCLUSION: Age, sex, smoking status, and comorbidities had no relation with the severity of COVID-19. HRCT severity score had moderate negative correlation with disease severity of COVID-19. HRCT severity score is also found to have moderate positive correlation with total neutrophil percentage, CRP, and D-dimer; and moderate negative correlation with total lymphocyte percentage. No correlation was also found between increasing CT severity score with the presence of comorbidities. HRCT severity...
A Prediction Model for Risk of Death in Kidney Transplant Recipients
CONCLUSIONS AND RELEVANCE: In this study, an accurate prediction model for mortality among kidney recipients, computable at the time of transplant, was developed and externally validated. Results suggest that this model may help stratify patient risk of death, allowing for improved medical decisions.
Adaptation of emergency surgical care during successive COVID-19 waves: a single-center analysis of surgically treated acute appendicitis
CONCLUSION: This long-term analysis suggests that the initial shift toward more advanced disease among patients undergoing appendectomy was not sustained, with presentation patterns and outcomes tending toward pre-pandemic levels during later pandemic waves. These findings may reflect adaptive processes within the healthcare system, despite ongoing external stress.
Trends in celiac disease autoimmunity before and after the COVID-19 pandemic
No abstract
Exploratory longitudinal cohort study of modest bilirubin-driven biochemical liver alterations after SARS-CoV-2 infection in a selected subgroup of patients with Wilson's disease and liver cirrhosis
CONCLUSIONS: SARS-CoV-2 infection was associated with persistent biochemical alterations, particularly elevated bilirubin levels of moderate magnitude in WD patients with cirrhosis, while global liver function parameters remained largely stable. These findings highlight the need for close post-infection monitoring of WD patients with cirrhosis, even in mild SARS-CoV-2 infections, to mitigate potential hepatic complications and guide ongoing management in this vulnerable population....
From Legacy to Innovation: A Comprehensive Review of Vaccine Platforms Against Viral Infections
Viral infections continue to pose a substantial global health concern, resulting in extensive morbidity and mortality among various populations. Although conventional vaccinations have been pivotal in managing and eliminating certain viral infections, the introduction of new viruses and the resurgence of existing ones underscore the ongoing necessity for creative immunization techniques. This review offers an extensive examination of both conventional and novel vaccine platforms for preventing...
Clinical effects of ursodeoxycholic acid in COVID-19 infection: a systematic review and dose-response meta-analysis
CONCLUSION: The findings support evidence for the clinical effects of UDCA for COVID-19 infection. There is a need for randomized trials to evaluate UDCA as a potential prophylactic agent against COVID-19.

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