Gastroenterology

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Clinical Knowledge Summaries- Gastrointestinal Topics

COVID-19 – PubMed search results

Vaccination rates remain low despite the influenza vaccine's proven safety and efficacy in protecting vulnerable groups, such as individuals diagnosed with liver disease. This cross-sectional study investigated influenza vaccination coverage, attitudes, beliefs, and influencing factors among 152 patients with liver disease in Greece. Over half (53.6%) were diagnosed with hepatitis, and 40.4% with cirrhosis. Overall, 58.6% of participants received the seasonal influenza vaccine. Multivariate...
CONCLUSIONS AND RELEVANCE: Gastroparesis is a condition of delayed gastric emptying without gastric outlet obstruction that is diagnosed based on a gastric emptying study. First-line treatments include a small particle diet and antiemetics and prokinetics. Severe refractory gastroparesis may be treated with procedures such as G-POEM or gastric electrical simulation.
CONCLUSIONS: This approach may enable more accurate estimates of vaccine efficacy and infection prevalence. In a spike-vaccinated population, anti-N antibody is more a potential specific marker for COVID-19 symptomatic disease than an ideal marker for SARS-CoV-2 infection. To our knowledge, this is the first preliminary report of identification of asymptomatic breakthrough infection from a well-vaccinated population using self-matched longitudinal pairs of serum samples.
BACKGROUND: Population-level epidemiological data on paediatric hepatobiliary diseases (HBD) are limited in Southeast Asia. We aimed to quantify national trends in healthcare utilisation, expenditure, and admission-based mortality associated with paediatric HBD in Thailand.
CONCLUSION: Sociodemographic and clinical factors influence consultation preferences in IBD. These findings may support equitable integration of remote care models.
Classical statistical estimators are limited by their reliance on deterministic data, making them ineffective when observations are imprecise or indeterminate. Neutrosophic statistics overcome this issue by giving observations in the form [Formula: see text] with 'a' denoting the determinate component and 'bI' representing the indeterminate component. In this paper, we present a novel neutrosophic estimator for estimating population mean under indeterminacy. The bias and mean squared error...
CONCLUSIONS: AlloHCT recipients achieve humoral immunity comparable to healthy individuals after three vaccine doses, supporting efficacy and safety of repeated SARS-CoV-2 vaccination in this vulnerable population.
CONCLUSIONS: Under the conditions of this study, synchronous remote teaching was associated with modest improvements in knowledge outcomes and with OSCE-assessed tendon reflex examination skill gains that were comparable to those of traditional in-person teaching, without statistically significant between-group differences in psychomotor performance. These findings do not establish durable skill acquisition and should not be interpreted as evidence of equivalence or superiority of synchronous...
BackgroundThe clinical characteristics and prognosis of acute kidney injury (AKI) in severe COVID-19 patients infected with the Omicron variant compared to patients with classic severe pneumonia remain unclear. This study aims to evaluate these differences following the adjustment of the "zero-COVID" policy.MethodsA retrospective cohort study was conducted using propensity score matching (PSM). We enrolled adult patients with non-COVID-19 severe pneumonia (2016-2021) and severe/critical COVID-19...
CONCLUSIONS: Zanubrutinib monotherapy produced substantial imaging-defined and clinical improvements in active glandular IgG4-RD without glucocorticoid induction. BTK inhibition was associated with modulation of B-cell differentiation states and downstream immune programmes, supporting its development as a steroid-sparing, non-B-cell-depleting therapeutic strategy.

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