Dermatology

Some books available in the Library

ABC of dermatology
Adverse drug reactions and the skin
An atlas of psoriasis
Atlas on dermatology
Atlas of pediatric dermatology
Clinical dermatology
Color atlas and synopsis of pediatric dermatology
Dermatology diseases and therapy
Dermatology: an illustrated colour text
Oxford handbook of medical dermatology

Search the Library Catalogue for more Dermatology books

DynaMed -Dermatology Topics (If you are not using Trust computer login with your OpenAthens)

COVID-19 and Skin – Pubmed search results

Autoimmune Manifestations Following COVID-19 Infection: A Systematic Review

Coronavirus disease 2019 (COVID-19) has been linked to immune dysregulation and autoantibody formation, raising concern that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may precipitate new-onset autoimmune disease. This systematic review synthesises controlled observational evidence on the incidence and risk of autoimmune manifestations following confirmed COVID-19. Following the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) 2020...

Trends in severe cutaneous adverse drug reactions before, during, and after the COVID-19 pandemic: A retrospective multicenter study of 794 cases

No abstract

Shear-Activated von Willebrand Factor Captures Extracellular Vesicles to Promote Platelet Activation and Metastasis

Plasma proteins are increasingly recognized as key regulators of extracellular vesicle (EV) behaviour in circulation. However, von Willebrand factor (vWF)-the largest multimeric glycoprotein in blood and the only blood protein activated by shear-has received little attention in this context. Under elevated shear stress, vWF transitions from a compact globular form to an extended adhesive conformation. Although elevated plasma vWF levels are associated with hypercoagulation in conditions such as...

Subungual hyperkeratosis as a diagnostic cue in crusted scabies

Crusted scabies is a severe and uncommon variant of Sarcoptes scabiei var. hominis infestation and typically arises in older adults with impaired cellular immunity. Secondary erythroderma and bacteremia are feared complications that may lead to increased morbidity. Herein, we report a case of crusted scabies with subungual involvement in a 65-year-old man with vascular dementia, schizophrenia, and chronic obstructive pulmonary disease presenting from an assisted living facility. At presentation,...

Deucravacitinib 5-Year Safety and Efficacy Results in Plaque Psoriasis: A Phase 3 Open-Label Extension of Randomized Clinical Trials

CONCLUSIONS: These findings demonstrate a consistent safety profile with no new safety signals and durable clinical response through 5 years of treatment with deucravacitinib.

Efficacy and safety of vunakizumab in patients with moderate-to-severe plaque psoriasis with a high drug interruption rate during the COVID-19 pandemic: a post hoc analysis from a single center of a phase III trial

During the phase III trial (NCT04839016), the outbreak of coronavirus disease 2019 (COVID-19) inevitably caused vunakizumab interruption in patients with psoriasis. This study extracted the data from Huashan Hospital, where almost all patients experienced drug interruption, and aimed to explore the efficacy and safety of vunakizumab in patients with moderate-to-severe plaque psoriasis and the impact of treatment interruption. A total of 90 patients with moderate-to-severe plaque psoriasis...

Pathogenicity of SARS-CoV-2 Omicron subvariants JN.1, EG.5.1, and BA.2.86.1 in immunologically naive cynomolgus macaques

Since the emergence of the SARS-CoV-2 Omicron variant, decreased morbidity and mortality relative to early strains have been widely reported. However, the virological characteristics of recent subvariants dominating the post-pandemic era remain to be fully elucidated. In the present study, the intrinsic pathogenicities of the Omicron subvariants JN.1, EG.5.1, and BA.2.86.1 were investigated using an immunologically naïve cynomolgus macaque model. All three variants exhibited robust replication...

Progressive isolated lower-lip oedema after mRNA COVID-19 booster complicated by methicillin-resistant Staphylococcus aureus superinfection: a necrotizing fasciitis mimic

Vaccine-related mucocutaneous reactions are usually mild, with atypical presentations and superinfections that can mimic soft-tissue emergencies. A previously healthy 19-year-old man developed isolated lower-lip oedema 3-4 h after an mRNA COVID-19 booster, peaking at 96 h. Initial blood test results were unremarkable, and angioedema therapy (antihistamines and a short course of corticosteroid) was ineffective. On day 12, he re-presented with marked swelling and necrotic slough but no systemic...

Real-World Evidence for the Impact of Minimal Disease Activity on Quality of Life in Atopic Dermatitis: An Interim Analysis of the Prospective, Multicenter, Non-Interventional UP-TAINED Study

CONCLUSION: Achieving MDA was associated with markedly improved QoL in real-world AD management, supporting MDA as a feasible and clinically meaningful treatment goal in routine practice.

Residual Burden in Adalimumab-Treated Patients with Hidradenitis Suppurativa: An Observational Cohort Study Based on Insurance Claims in the USA

CONCLUSION: While adalimumab improved certain outcomes in HS, residual burden and high discontinuation rates indicate the need for accessible and durable therapies.

Immune Divergences Between the Skin Sensitizer 2,4-Dinitrochlorobenzene and the Respiratory Sensitizer Phthalic Anhydride Revealed by Mouse Single-Cell Transcriptomics

CONCLUSION: A distinct transcriptomic signature was identified in immune cells during sensitization to DNCB or PA in this study.

A randomized, double-blinded trial to evaluate two therapeutic foods as adjunctive therapies in dogs with environmental and/or food induced atopic dermatitis

This study evaluated changes in pruritus, skin lesions, and gastrointestinal signs (G) in dogs fed a positive Control food, Hill's Prescription Diet d/d Potato & Venison (Hill's Pet Nutrition, Topeka, KS, USA) compared to a Test food, Hill's Prescription Diet Derm Complete (Hill's Pet Nutrition, Topeka, KS, USA), over an eight-week period. We hypothesized that feeding either food would result in improvements in skin lesions and pruritus when compared to baseline while maintaining positive GI and...

Treatment of canine otitis externa: a randomized, double-blinded, clinical field study comparing the hydrocortisone aceponate monotherapy to a multi-agent reference product

Erythemato-ceruminous otitis externa (ECOE) is a canine inflammatory condition very frequently involving secondary microbial infections. This multicentric, masked, randomized, clinical field trial in Japan evaluated the efficacy and safety of a hydrocortisone aceponate (HCA) spray solution (Cortotic™, Virbac, France) compared to a terbinafine/florfenicol/betamethasone acetate ear gel (Osurnia™, Bussan Animal Health CO Ltd, Japan) in 200 dogs with ECOE (OTIS3 ≥ 5). Dogs received either Cortotic™...

Deep phenotyping of infants and toddlers undergoing food oral immunotherapy (DINOSAUR): design and baseline characteristics of a prospective multi-omics cohort

CONCLUSIONS: This prospective cohort study is the first of its kind to employ a systems biology approach to investigate how extensive biological and environmental factors influence OIT outcomes.

Artificial intelligence in trichology: A systematic review of current applications in diagnosis, severity assessment, and treatment monitoring

CONCLUSIONS: AI demonstrates promising potential for scalp disease diagnosis and objective severity quantification, particularly for automated SALT estimation and patterned hair-loss assessment. However, the current evidence base is dominated by retrospective single-source datasets with limited external validation, restricting confidence in generalizability and clinical implementation.

RUCAM-ascertained immunology and autoimmunity specifics of six idiosyncratic drug-induced liver injury types with refined classification: their individual complex molecular interplay

Idiosyncratic drug-induced liver injury (iDILI) is not a uniform disease but rather includes a variety of types based on immune, autoimmune, and clinical considerations. This review attempts to close information gaps regarding the role of immunity and autoimmunity involved in the different iDILI disease types. The analysis of the current literature focusing on iDILI reveals compelling evidence of a pivotal role of immunity or autoimmunity in various types of iDILI. Among the autoimmune-triggered...

Phenytoin-induced drug rash with eosinophilia and systemic symptoms syndrome in a child: A rare but serious adverse drug reaction

Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome is a rare, potentially fatal adverse drug reaction (ADR) most associated with anticonvulsants. Paediatric cases are uncommon and may present with atypical or early onset, posing diagnostic challenges. We report the case of a 10-year-old boy who developed high-grade fever, generalized maculopapular rash, lymphadenopathy, eosinophilia, and hepatic involvement shortly after initiation of phenytoin for epilepsy. Infectious causes...

Physiological Characteristics of Scalp Skin With High Sebum Production and the Impacts of Shampoo Cleansing

CONCLUSION: This study underscores the significance of sebum levels and composition in scalp health among Chinese individuals, emphasizing the need for shampoos that remove excess sebum while preserving the scalp barrier.

Prevalence of contact sensitisation among patients with hand eczema and factors associated with contact sensitisation and disease severity

CONCLUSION: Patch test sensitisation was common in hand eczema patients. Polysensitisation was associated with use of cosmetics. Use of non-permeable gloves may worsen hand eczema.

Redefining Treat-to-target in Atopic Dermatitis: Towards Meaningful, Patient-centred Disease Control - An ISAD Position Paper

Treat-to-target strategies link predefined goals to regular assessment and treatment adaptation. In atopic dermatitis, recent initiatives have mainly defined thresholds using clinician- and patient-reported outcomes. This review and position paper critically examines current approaches and proposes priorities for a more clinically meaningful, patient-centred and globally applicable framework. It synthesizes recent consensus and outcome-harmonization initiatives with selected lessons from...

Recent articles from selected Journal RSS feeds

British Journal of Dermatology (full-text available via NHS Athens)

Content validity of the Recap of atopic eczema (RECAP) instrument in Dutch, English and German to measure eczema control in young people with atopic eczema: a cognitive interview study

Is routine laboratory testing in healthy young patients taking isotretinoin necessary: a critically appraised topic

Factors associated with treatment satisfaction in patients with hidradenitis suppurativa: results from the Global VOICE project

Patient satisfaction with treatment for hidradenitis suppurativa

Germline intergenic duplications at Xq26.1 underlie Bazex–Dupré–Christol basal cell carcinoma susceptibility syndrome

对癌症治疗中使用的免疫检查点抑制剂的皮肤反应

Living with vulval lichen sclerosus: a qualitative interview study

Mirikizumab 治疗银屑病的有效性和安全性

Clinical associations and classification of immune checkpoint inhibitor‐induced cutaneous toxicities: a multicentre study from the European Academy of Dermatology and Venereology Task Force of Dermatology for Cancer Patients

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