Pain interferes with daily activities and undermines people’s ability to engage in treatment for opioid use disorder. Yet barriers to assessment and treatment of pain persist.
Author: Zu-In Su, Carlos Blanco, Tisha Wiley, Nora D. Volkow
Posted: June 27, 2026, 12:00 am
In a cluster-randomized trial involving patients having major noncardiac surgery, tranexamic acid reduced the need for red-cell transfusion during hospitalization and was noninferior to placebo for venous thromboembolism within 90 days.
Author: Brett L. Houston, Daniel I. McIsaac, Rodney H. Breau, Salmaan Kanji, Peter Greenstreet, Meghan Andrews, Sinziana Avramescu, Hema S. Bagry, Robert Balshaw, Jayesh Daya, Kaitlin Duncan, Christopher C. Harle, Eric Jacobsohn, Tina Kerelska, Marshall Pitz, Paul Komenda, Sarah McIsaac, Tim Ramsay, Tarit Saha, Alan Tinmouth, Angela Recio, Daniel Szoke, Marshall Tenenbein, Sarah Slagerman, Dayna Solvason, Robert Talarico, Dean A. Fergusson, Ryan Zarychanski
Posted: June 25, 2026, 12:00 am
The EPA has decided to stop considering the monetary value of public health benefits in federal rulemaking related to air pollution. This decision could have profound health consequences.
Author: Arianne Teherani, Rupa Basu, Sheri Weiser
Posted: June 25, 2026, 12:00 am
Though Medicare is launching the GLP-1 Bridge program, offering enrollees temporary discounted access to GLP-1 medications for weight loss, the long-term model to which it was meant to lead was postponed.
Author: Stacie B. Dusetzina
Posted: June 25, 2026, 12:00 am
When patients who have become homeless show a physician photos of themselves in better times, they are, in part, asking to be treated fairly, like they are people who might still turn their lives around.
Author: Kathryn Taylor
Posted: June 25, 2026, 12:00 am
Every year, many millions of surgical patients worldwide are unnecessarily exposed to a higher-than-necessary risk of blood transfusion because they do not receive a single dose of tranexamic acid just before the surgery. This failing is due not to a lack of high-quality scientific evidence on the overall safety, efficacy,...
Author: Michael F. Murphy, Ian Roberts
Posted: June 25, 2026, 12:00 am
The ripple effects of U.S. anti-DEI policies extend far beyond individual labs: scientific discovery is slowing, early-career investigators are reconsidering their futures, and the pipeline of medical school applicants is shifting in real time.
Posted: June 25, 2026, 12:00 am
Without deliberate efforts to evaluate long-acting injectable ART in the populations that need these therapies most, their benefits may accrue primarily to people who are well served by existing systems.
Author: Jonathan Falconer, Linda-Gail Bekker, Joseph N. Jarvis
Posted: June 24, 2026, 12:00 am
Divergent approaches to psychedelics regulation have led to an environment in which patients, clinicians, and policymakers face conflicting expectations about access, safety, and clinical responsibility.
Author: Marcus Hughes
Posted: June 18, 2026, 12:00 am
Amid continuing regulatory discussion, the field of psychedelic medicine faces a choice about how to conceptualize and implement treatments.
Author: Yaara Zisman-Ilani, Rachel Yehuda
Posted: June 18, 2026, 12:00 am
A family physician who has worked hard to help far too many patients recover from opioid addiction finds himself judged harshly by a system that once encouraged aggressive pain control.
Author: James C. Wilson III
Posted: June 18, 2026, 12:00 am
Observations in Down syndrome were critical to Alzheimer’s disease discoveries. But persons with Down syndrome have historically been excluded from trials relying on insights derived from their biology.
Author: Michael S. Rafii
Posted: June 18, 2026, 12:00 am
The lack of vaccines and disease-specific therapeutics for Bundibugyo Ebola has dramatically affected the community’s perception of Ebola treatment centers. In this context, trust becomes critical.
Author: Serge Tonen-Wolyec, Laurent Bélec
Posted: June 17, 2026, 12:00 am
Recent lawsuits against social media companies, like past litigation against drug and tobacco manufacturers, show that when other branches of government fail to protect public health, the courts can help.
Author: Jerry Avorn
Posted: June 17, 2026, 12:00 am
If the current cholera pandemic, which began in 1961, is ever to end, the world will need better cholera vaccines that are effective in young children and global access to safe water and adequate sanitation.
Author: Edward T. Ryan, Firdausi Qadri, Julia A. Lynch
Posted: June 11, 2026, 12:00 am
Despite recognition that racial and ethnic categories are poor proxies for genetic diversity, race is still used to guide pharmaceutical use, posing risks of ineffectively low or dangerously high dosing.
Author: Harsimar K. Ahuja, David S. Jones, Winfred W. Williams
Posted: June 11, 2026, 12:00 am
We now know that humans are more than 99.9% genetically alike. So why does medicine still link certain diseases to race? And what do genetics actually tell us about race, ancestry, and disease?
Posted: June 11, 2026, 12:00 am
Corporatization in health care doesn’t have a single cause. But predictable harms often arise in circumstances in which market discipline is lacking and policies make consolidation especially profitable.
Author: Loren Adler
Posted: June 4, 2026, 12:00 am
Increasingly, in the age of corporate medicine, the fundamental values of U.S. health system leaders and clinicians are diverging, to the detriment of trust, communication, morale, and patient care.
Author: Louise Aronson
Posted: June 4, 2026, 12:00 am
Vaccine hesitancy is often driven by safety concerns. Clinician recommendations, presumptive communication, and empathy improve uptake; maintaining trust supports future acceptance and community protection.
Author: Sean T. O’Leary, Margie Danchin
Posted: June 4, 2026, 12:00 am