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Gastroenterology

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Big 4 Medical Journals

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Clinical Knowledge Summaries- Gastrointestinal Topics

COVID-19 – PubMed search results

A Pilot Validation Study of Plant-Based and Allergy-Friendly Alternative for Testing Gastric Emptying: A Randomized Trial in Healthy Participants
CONCLUSIONS AND INFERENCES: The vegan meal demonstrated in vitro stability, in vivo performance comparable to the egg meal, and a COV(intra) of 18.8%, which was lower than the 23.8% reported in repeat egg meal GE studies.
Post-COVID-19 Muscle Weakness and Recovery Patterns After Mild-to-Moderate Infection: A Retrospective Analysis of a Structured Rehabilitation Program Using the MRC Scale
Background/Objectives: Post-COVID-19 muscle weakness is common even after mild or moderate infection, driven by systemic inflammation, prolonged inactivity, and reduced functional reserve. This study aimed to describe changes in global muscle strength assessed using the Medical Research Council (MRC) scale in adults recovering from mild or moderate COVID-19 who participated in a structured two-week rehabilitation program, and to compare these changes with those observed under standard medical...
Predictors of Severe Outcomes in COVID-19: Evidence from Real-World Multicenter Retrospective Study (2020-2024)
Background/Objectives: This study analyzed demographic, clinical, laboratory, and outcome data from patients hospitalized with Coronavirus disease 2019 in eastern Poland between March 2020 and December 2024. This study aimed to assess sex-related differences in clinical features, treatments, and outcomes, and to identify predictors of mortality and mechanical ventilation in hospitalized patients. Methods: A retrospective cohort of 2811 adults hospitalized across four infectious disease centers...
Combined HBsAg and anti-HBc testing is required to estimate hepatitis B virus seroprevalence in a low-endemic country: findings from a nationwide population-based serosurvey, Belgium, 2020
BACKGROUNDThe World Health Organization aims to eliminate hepatitis B virus (HBV) by 2030 through reducing incidence and mortality. Accurate prevalence estimates are crucial to guide policies and monitor progress towards HBV elimination. However, HBV prevalence can be overestimated when relying solely on hepatitis B surface antigen (HBsAg) because of unconfirmed or false-positive results. Robust screening algorithms to improve diagnostic accuracy and minimise false positives are required.AIMWe...
A cross-continental comparative analysis of the neurological manifestations of Long COVID
CONCLUSION: Neuro-PASC presents globally but symptom burden, and psychological distress vary across regions, likely influenced by sociocultural factors, healthcare access, and diagnostic tools. These findings highlight the need for culturally-adapted screening and post-COVID care worldwide.
Integrated long-term safety of 10-year ozanimod treatment: results from clinical trials in patients with moderate-to-severe ulcerative colitis or relapsing multiple sclerosis
CONCLUSIONS: Long-term exposure to ozanimod is well tolerated in patients with moderate to severe UC or RMS, confirming the previously established safety profile of ozanimod.
COVID-19 vaccination hesitancy amongst inflammatory bowel disease patients
No abstract
Trends and inequities in peptic ulcer mortality across the United States, 1999-2023
CONCLUSIONS: PUD mortality declined over a 25-year period but plateaued or increased in selected strata in the late 2010s and during the pandemic. Findings support sustained H. pylori control, evidence-based gastroprotection for high-risk medication users, and timely endoscopy-especially for older adults, men, rural residents, and regions with a high burden. Continuous surveillance should monitor post-pandemic rebound risks and equity in access.
Patterns of specialist healthcare delivery among inflammatory bowel disease patients in response to the COVID-19 pandemic in Ontario: a population-based study
CONCLUSIONS: During the COVID-19 pandemic, the rapid transition from in-person to virtual IBD specialist care led to a slight increase in overall IBD visits. There was also a small decrease in the gap in rates of IBD specialist visits between high- and low-access regions.
Status and outlook of mRNA therapeutics for viral diseases
Endemic and emerging viral diseases continue to impose significant health, economic, and societal burdens worldwide. Vaccines and therapeutics represent two key pillars in the fight against these threats. Since the clinical success of mRNA vaccines during the COVID-19 pandemic, mRNA therapeutics have rapidly evolved from a niche innovation into a validated and versatile medical platform. While early efforts focused primarily on vaccine development, recent advances have expanded the scope to...

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