Gastroenterology
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COVID-19 – PubMed search results
Background/Objectives: Perforated peptic ulcer (PPU) represents a surgical emergency with substantial morbidity and mortality. Despite declining overall peptic ulcer disease (PUD) incidence, contemporary population-based data comparing outcomes between perforated and non-perforated PUD remain limited, particularly during the COVID-19 pandemic. This study aimed to characterize the clinical and economic burden of PPU and identify independent predictors of adverse outcomes. Methods: We conducted a...
CONCLUSIONS: These preliminary findings suggest that social exclusion and physical inactivity may be more strongly associated with self-perceived distress than dietary challenges in contexts where GF food access is structurally protected. Results are exploratory, hypothesis-generating, and should not be generalised beyond this selected Italian cohort.
Infections remain a leading cause of morbidity and mortality in patients with cirrhosis and liver transplantation (LT). Vaccination is underutilized despite proven benefits, and responses are often blunted by cirrhosis-associated immune dysfunction and post-transplant immunosuppression. This review synthesizes current evidence and recent advances in vaccination strategies for adult LT recipients, emphasizing optimal timing, novel vaccine platforms, and precision vaccinology. We discuss emerging...
The post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID, represent a multifaceted challenge in pediatric populations, characterized by symptoms persisting beyond the acute phase. In Taiwan, where early public health measures initially contained the pandemic, the 2022 Omicron surge prompted focused investigation into pediatric PASC, highlighting the critical need for longitudinal data in this specific demographic. To address this challenge, the Diagnosis and Support for COVID...
CONCLUSIONS: Comparable neutralizing responses across JN.1 lineage variants suggest that annual COVID-19 strain updates targeting variants with small differences within the same antigenic cluster may have limited impact on vaccine-induced protection. These findings may inform future public health policy and regulatory decision-making for COVID-19 vaccines.
CONCLUSIONS: ALD recipients show excellent and improving survival, while MASH recipients' declining survival highlights the need for better risk stratification and management.
CONCLUSIONS: Pre-infection UDCA use was not associated with reduced risk for most long COVID outcomes in patients with SLD. The observed associations warrant cautious interpretation given potential residual confounding and surveillance bias.
Many individuals hospitalized due to severe viral infections develop mental and physical sequelae, which could potentially be prevented by targeted interventions for those at risk. Our goal was to develop and externally validate an algorithm for predicting mental and physical symptoms after SARS-CoV-2 hospitalization utilizing routinely collected clinical data. Participants were included from two independent samples of the German National Pandemic Cohort Network (NAPKON): a model development...
INTRODUCTION: Conforming to the global commitment of combating viral hepatitis by 2030, India launched the National Viral Hepatitis Control Program (NVHCP) in 2018. NVHCP is a comprehensive strategy that uses a cascade of care approach to tackle all forms of viral hepatitis. This study was conceptualized to assess the implementation status of NVHCP and to understand the key stakeholders' perspective on prevention, screening, diagnosis, and treatment of viral hepatitis in Uttarakhand.
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