{"id":201,"date":"2013-06-18T08:51:17","date_gmt":"2013-06-18T08:51:17","guid":{"rendered":"http:\/\/www.library.wmuh.nhs.uk\/wp\/?page_id=201"},"modified":"2013-10-25T10:06:14","modified_gmt":"2013-10-25T10:06:14","slug":"obstructive-lung-disease-results-from-pubmed","status":"publish","type":"page","link":"https:\/\/www.library.wmuh.nhs.uk\/wp\/other-updates\/respiratory-medicine\/obstructive-lung-disease-results-from-pubmed\/","title":{"rendered":"Obstructive Lung Disease Results from Pubmed"},"content":{"rendered":"<style>\nh3.hungryfeed_feed_title {}\ndiv.hungryfeed_feed_description {}\ndiv.hungryfeed_feed_content {}\ndiv.hungryfeed_items {}\ndiv.hungryfeed_item {margin-bottom: 10px;}\ndiv.hungryfeed_item_title {font-weight: bold;}\ndiv.hungryfeed_item_description {}\ndiv.hungryfeed_item_author {}\ndiv.hungryfeed_item_date {}\n<\/style>\n<script type=\"text\/javascript\">\n\/\/ Custom Javascript here...\n<\/script>\n<div class=\"hungryfeed_items\">\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42164240\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Contextual fear conditioning leads to hypo-innervation of the left ventricular myocardium in female but not male C57BL\/6J mice<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: Contextual fear conditioning had a profound morphological effect on the innervation of the left ventricular myocardium of female but not male mice. This may have implications for cardiac function in female patients with anxiety disorder and requires further investigation.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Luca M Lautenschl\u00e4ger<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 21, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42167772\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Mucoactive therapies and the European Respiratory Society guideline for adult bronchiectasis: what now after the CLEAR trial?<\/a><\/div>\n<div class=\"hungryfeed_item_description\">No abstract<\/div>\n<div class=\"hungryfeed_item_author\">Author: James D Chalmers<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 21, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42159704\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Phase-resolved functional lung MRI detects single-dose and sustained bronchodilator responses in COPD in a randomized crossover trial<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: PREFUL MRI sensitively captured immediate SD T\/O-induced improvements in V\/Q parameters and dose-dependent PWV responses after sustained bronchodilation.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Andreas Voskrebenzev<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 20, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42153326\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Single-cell Sequencing Unveils A Profibrotic Macrophage and Infiltrating Monocyte Niche in the Bronchoalveolar Lavage of Patients with Chronic Obstructive Pulmonary Disease<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS: The immune cell transcriptomic profile of COPD BAL reveals global immune dysregulation, with increased abundance of proinflammatory and profibrotic macrophages, monocytes and neutrophils, potentially driving airway remodeling. Regulatory T cells may play a significant role in gas exchange perturbations of COPD.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Firoozeh V Gerayeli<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 19, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42155496\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Comorbid diabetes disease severity and microbial changes in patients with bronchiectasis: a combined analysis of data from the EMBARC, EMBARC-India, Australian, and BE-China registries<\/a><\/div>\n<div class=\"hungryfeed_item_description\">BACKGROUND: Bronchiectasis and diabetes commonly coexist and are associated with immune dysfunction and increased susceptibility to infection. Although diabetes is associated with worse prognosis in cystic fibrosis-related bronchiectasis, data are scarce for its impact on non-cystic fibrosis bronchiectasis. This study aimed to characterise the impact of diabetes on clinical outcomes and microbial and inflammatory profiles in patients with bronchiectasis.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Rebecca C Hull<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 19, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42151044\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Developing and Validating the Long COVID-19 Symptom Severity Index (LCSSI) for Patients With Chronic Obstructive Pulmonary Disease<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS \/ IMPLICATIONS FOR PRACTICE: Based on this sample, the results indicate the LCSSI has acceptable internal consistency and validity, supporting its use as a reference tool for symptom assessment in patients with COPD during the late recovery phase for Long COVID.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Ling-Chan Pan<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 18, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42143630\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Life Expectancy in Chronic Obstructive Pulmonary Disease<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS AND RELEVANCE: In this cohort study, COPD was associated with lower life expectancy, including in adults who never smoked.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Surya P Bhatt<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 17, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42136984\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Fine Particulate Exposure During Pregnancy Impacts on Perinatal Complications in Deeply Phenotyped Preterm Infants With Significant Immaturity<\/a><\/div>\n<div class=\"hungryfeed_item_description\">The identification of ubiquitous risk factors determining long-term morbidity is crucial in infants born prematurely when aiming to develop prevention strategies. In a cohort of deeply phenotyped infants born before 32 weeks gestational age, we successfully demonstrate that exposure to fine particulate matter during pregnancy is associated with increased odds of preeclampsia and altered birth weight percentiles, highlighting potential underlying effects on vascular and metabolic pathology in...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Caroline Johansson<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 15, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42134984\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Nasal nitric oxide combined with clinical features for preliminary screening of primary ciliary dyskinesia in bronchiectasis<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS: Patients with PCD had more severe disease, reinforcing the need for structured screening in patients with bronchiectasis. nNO combined with clinical features is an effective and reliable screening strategy for PCD in bronchiectasis.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Shunlian Hu<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 14, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42121868\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Mast Cells in the Brain: Enduring Mysteries, Emerging Roles<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Mast cells are heterogeneous, tissue-resident immune sentinels best known for their roles in allergy and peripheral inflammation. The discovery of mast cells within the meninges and brain parenchyma over a century ago raised enduring questions regarding their function in the central nervous system (CNS), their ontogeny, and distinction from peripheral counterparts. Brain mast cells are sparse and predominantly located in perivascular niches rather than forming dense aggregates, a feature that...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Shivani Mandal<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 13, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42125477\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Pre-diagnosed sleep apnoea is linked to severe courses in community-acquired pneumonia<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: Our results highlight SDB as a potential novel risk factor for severe courses of CAP, including the need for ICU and MV. It suggests that SDB should be considered a critical component in the risk stratification and management of CAP and that established CPAP treatment may have a protective effect. Additional study data are needed to further substantiate these findings.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Thomas Bitter<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 13, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42128767\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>EPIMETRIC: A cfDNA Methylation-Based Algorithm for COPD Diagnosis and Stratification<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS: EPIMETRIC represents the first blood-based cfDNA methylation signature for COPD diagnosis and GOLD stratification. It provides a minimally invasive and highly accurate tool for early detection, personalized treatment, and identification of high-risk patients.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Abel Garcia-Diaz<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 13, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42116095\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Impact of post-exertional malaise frequency and fatigue in Long COVID patients on health-related quality of life<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: Both PEM frequency and PEM severity substantially impair HRQoL in individuals with Long COVID. These findings underscore the clinical relevance of PEM as a key symptom and highlight the need for targeted management strategies to mitigate its impact on daily life.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Theresa Th\u00f6lking<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 12, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42115292\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Transcriptional landscape of pulmonary artery endothelium reveals subpopulation- and disease-specific remodeling signatures<\/a><\/div>\n<div class=\"hungryfeed_item_description\">The physiological state of endothelial cells (ECs) is a central determinant of organ health. Distinct endothelial phenotypes and transcriptional programs are linked to vessel size and anatomical location, but it remains unclear how this intrinsic heterogeneity is organized within a particular niche. We performed compartment-specific single-cell profiling of human pulmonary artery (PA) ECs from healthy donors and from patients with two clinically divergent forms of pulmonary hypertension (PH):...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Thomas Lins<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 11, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42111370\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>The construct validity of real-world digital mobility outcomes in people with COPD<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS: Construct validity was supported for all walking activity (amount and pattern) DMOs, and most of the gait (pace, rhythm, and bout-to-bout variability) DMOs, indicating the clinical utility of these measures.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Dimitrios Megaritis<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 11, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42102198\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>The pleuroparenchymal fibroelastosis atlas reveals aberrant cell states and their zonation as an alternate roadmap to lung fibrosis<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Pleuroparenchymal fibroelastosis (PPFE) is a progressive interstitial lung disease (ILD) with defining histology of intra-alveolar fibrosis with septal elastosis (AFE), suggesting unique cellular disease processes. Here, we present a binational single-nucleus RNA sequencing atlas of PPFE, based on explanted lungs from 40 patients. Immunofluorescence microscopy, RNA in situ hybridization, micro-computed tomography (CT), and hierarchical phase-contrast (HiP) synchrotron CT provided spatial...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Jannik Ruwisch<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 8, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42092985\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Extracorporeal membrane oxygenation without invasive mechanical ventilation for acute respiratory distress syndrome: an international cohort study<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS: Patients selected for 'primary awake ECMO' and 'extubated ECMO' presented different baseline characteristics, strategy failure, and 90-day mortality rates. However, strategy failure was consistently associated with 90-day mortality in both groups.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Roberto Roncon-Albuquerque<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 7, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42094222\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>An index of maximal expiratory flow-volume curve with different features related to central and peripheral concavity<\/a><\/div>\n<div class=\"hungryfeed_item_description\">The obstructive index, a quantitative maximal expiratory flow-volume curve index correlated with central and peripheral concavity, reflecting the extent of emphysema on chest computed tomography in subjects with obstructive lung disease https:\/\/bit.ly\/495OwFz.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Fumi Mochizuki<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 7, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42097909\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>ECFS statement on theratyping and theranostics in the context of rare and ultrarare CFTR variants in people with CF<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Genotype-based drug development has yielded highly effective therapies, notably the triple combinations elexacaftor\/tezacaftor\/ivacaftor (ETI) and vanzacaftor\/tezacaftor\/deutivacaftor (VTD), now approved in Europe for people with CF having at least one non-class I variant. However not all these people with CF will respond to ETI or VTD, and a few not under the label may respond. Facilitating opportunities to access for patients with rare variants has required a shift in paradigm toward...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Kris De Boeck<\/div>\n<div class=\"hungryfeed_item_date\">Posted: May 7, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42048592\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Quantitative Phase-resolved Functional Lung MRI Prediction of Disease Progression in Connective Tissue Disease-associated Interstitial Lung Disease<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Background Connective tissue disease-associated interstitial lung disease (CTD-ILD) is a spatially and temporally heterogeneous disease. Determining whether CTD-ILD is in a progressive stage is crucial for guiding clinical management. Purpose To determine whether CTD-ILD is associated with ventilation and perfusion parameters quantified with phase-resolved functional lung (PREFUL) MRI and whether these functional parameters can help predict CTD-ILD progression. Materials and Methods In this...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Tao Ouyang<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 28, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42049788\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Inhaled corticosteroid overuse and deprescribing eligibility in COPD (iCODEC Study): a nationwide cross-sectional analysis in China<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Inhaled corticosteroid (ICS) overuse is common in chronic obstructive pulmonary disease (COPD) and associated with substantial adverse effects. Deprescribing has emerged as a strategy to optimize therapy, yet large-scale evidence on the prevalence and associated factors of eligibility for ICS deprescribing is limited. This nationwide cross-sectional study analyzed data from the Cough and Wheeze Pharmaceutical Care Clinics database between January 2021 and September 2024. Patients aged \u226540 years...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Changcheng Shi<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 28, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42049798\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Investigating sarcopenia and mucus plugging by chest computed tomography in patients with severe chronic obstructive pulmonary disease<\/a><\/div>\n<div class=\"hungryfeed_item_description\">To determine the relationship between mucus plugging and CT-derived parameters of sarcopenia in routine chest CT-scans. Patients with advanced Chronic Obstructive Lung Disease (COPD GOLD 3 or 4) were investigated. Mucus plug score (MPS) and cross-sectional muscle area (CSA) of pectoralis and erector spinae muscle of each patient was assessed by two radiologists. Statistics included non-parametric group comparison, multivariate analysis, and inter- and intrarater agreement. Median age of 123...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Antonia Petersen<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 28, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42050186\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>The role of cytotoxicity in the process of carcinogenesis<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Enhanced cancer prevalence findings restricted to high, cytotoxic dose levels in long-term animal cancer studies are generally assumed to be a consequence of-indirect or secondary-mutational effects, e.g. DNA damage mediated by generation of reactive oxygen species (ROS) or replication errors occurring during regenerative cell proliferation. An alternative explanation is provided by recent findings suggesting that cell lysis caused by cytotoxic doses of non-genotoxic agents may give rise to...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Michael Schwarz<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 28, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42050294\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>CT-based lung ventilation metrics: reference ranges and pulmonary function test correlations in healthy individuals<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: CT-derived ventilation correlates strongly with PFT-indices but yields lower absolute values. Demographic and anatomical factors significantly influence ventilation distribution. These normative data provide a reference framework for clinical functional lung assessment.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Charlotte E van den Berg<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 28, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42040563\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Analysis of risk factors for the development of bronchiolitis obliterans in children with severe &lt;em&gt;Mycoplasma pneumoniae&lt;\/em&gt; pneumonia<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: The risk of bronchiolitis obliterans is greater in children with severe Mycoplasma pneumoniae at a younger age, with combined viral infections, and with manifestations such as the three-concave sign, pulmonary atelectasis, and bronchiectasis, and we should be vigilant for bronchiolitis obliterans so that early diagnosis can be made and timely intervention can be performed to treat the disease.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Jiapu Hou<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 27, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42044645\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Azurocidin-1 as a mediator of bronchiectasis severity, epithelial defence, and target of dipeptidyl peptidase-1 inhibition: an international, multicohort study<\/a><\/div>\n<div class=\"hungryfeed_item_description\">BACKGROUND: Dipeptidyl peptidase-1 (DPP1) inhibitors prevent the activation of neutrophil serine proteases and reduce exacerbations in people with bronchiectasis. We previously identified a novel effect of DPP1 inhibitors in reducing the neutrophil pseudoenzyme azurocidin-1 (AZU1). The aim of this study was to investigate the role of AZU1 in the pathophysiology of bronchiectasis.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Amelia Shoemark<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 27, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42038865\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Effect of Enhanced Psychological Nursing Combined with Graded Pulmonary Rehabilitation in Elderly Patients with COPD: A Randomized Controlled Trial : Effect of Enhanced Psychological Nursing in Elderly Patients with COPD<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: Incorporating targeted psychological support and a graded pulmonary rehabilitation strategy yields substantial benefits in emotional well-being, pulmonary performance, adherence levels, and life quality in elderly COPD patients. This comprehensive care model may serve as an effective approach for sustained disease management in this population.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Leping Zhang<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 27, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42045582\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Photon-counting CT for dynamic lung perfusion: validation of a low-dose protocol in a porcine lung transplantation model<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: Dynamic PCCT enables quantitative lung perfusion imaging at radiation doses comparable to standard chest CT. Low-dose dynamic PCCT shows strong agreement with reference-dose acquisitions, while dynamic parameters reveal functional differences not captured by static PBV imaging.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Anna M Hunkem\u00f6ller<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 27, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42044658\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Tuberculous mastitis: A rare manifestation of extrapulmonary tuberculosis<\/a><\/div>\n<div class=\"hungryfeed_item_description\">We present the case of a 39-year-old Indian female patient diagnosed with tuberculous mastitis and lymph node tuberculosis. The patient had a history of tuberculosis infection treatment as a newborn. She initially presented with symptoms including fever, weight loss, and coughing. Clinical examination revealed a newly developed mass in the right breast. Diagnostic workup included an 18F-FDG PET-CT scan, followed by repeated biopsies. Microbiological culture, molecular testing, and...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Friederike Dellbr\u00fcgge<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 27, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42029914\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Photon-counting CT vs V\/Q SPECT for lobar perfusion quantification in chronic thromboembolic pulmonary hypertension<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: PCCT-based perfusion imaging shows high concordance with V\/Q-SPECT in this cohort, supporting its feasibility as a single-modality tool for functional and anatomical lung evaluation in CTEPH.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Matthias M V Moeskes<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 24, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42021779\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Comparison of Tools for Nutrition Assessment in Stable Subjects with Chronic Obstructive Pulmonary Disease: Which is the Best Mortality Predictor in Real Clinical Practice?<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: Among five simple nutritional assessment tools, only PNI independently predicted long-term mortality in stable COPD. Given its simplicity, objectivity, and reliance on routinely available laboratory parameters, PNI appears to be a practical marker to support risk stratification and guide proactive management in outpatient COPD care.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Koichi Nishimura<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 23, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42023426\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>VENTILATORY INEFFICIENCY REVEALS EMERGENT PaCO(2) EQUILIBRIUM DURING EXERCISE IN OBSTRUCTIVE LUNG DISEASE<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Ventilatory \"inefficiency\" during exercise in obstructive lung disease-such as that resulting from increased dead space or ventilation-perfusion mismatch-is commonly interpreted as a perturbation that requires an additional increase in minute ventilation and thus in V\u0307E\/V\u0307CO(2) to preserve PaCO(2) homeostasis. This observation raises a fundamental question: how could an increase in V\u0307E\/V\u0307CO(2) during exercise be actively directed toward defending PaCO(2) stability if no known neural signal,...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Philippe Haouzi<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 23, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42007151\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Predictive value of quantitative CT-derived emphysema heterogeneity for outcomes following bronchoscopic lung volume reduction<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: Quantitative CT-derived assessment of emphysema heterogeneity provides a strong and clinically significant predictor of treatment response to bronchoscopic lung volume reduction.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Wenjin Zhang<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 20, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/42001976\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>YouTube as a source of information on the non-pharmacological treatment of COPD<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: YouTube videos on non-pharmacological treatment of COPD are of high quality; however, nutrition-focused misinformation is widespread and tends to attract disproportionately high engagement.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Sara Kl\u00f6czl Kring<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 19, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41988279\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Radiomics differences between GOLD I-II and GOLD III-IV in patients with chronic obstructive pulmonary disease<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS: Collectively, a noticeable difference in radiomics features was observed between GOLD I-II and GOLD III-IV patients with COPD. The computed tomography (CT)-based radiomics features, original_firstorder_10Percentile and wavelet.LHL_glszm_GrayLevelVariance, can be potentially used to evaluate the severity of COPD patients. However, our results require further validation through multicenter and large-scale clinical studies.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Zhiwei Li<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 16, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41991206\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>The Impact of Neighborhood Material and Social Disadvantage on Respiratory Health Across Canada<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS: Residence in the most materially and socially disadvantaged neighborhood is associated with worse lung function and exercise outcomes, highlighting a population particularly vulnerable to chronic airways diseases.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Mira A Russell<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 16, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41975783\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Preoperative Pulmonary Rehabilitation and Perioperative Outcomes in High-Risk COPD Patients Undergoing Lung Cancer Surgery: A Retrospective Cohort Study<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Background\/Objectives: Chronic obstructive pulmonary disease (COPD) coexists with lung cancer in 40-70% of cases and increases perioperative risk, particularly in patients with severely impaired pulmonary function. Preoperative pulmonary rehabilitation (PR) has been proposed as a perioperative optimization strategy; however, its effect on hospital length of stay (LOS) in patients with advanced COPD remains unclear. This study aimed to compare postoperative complications, intensive care unit...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Kubilay \u0130nan<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 14, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41979097\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Comparison of AI-based Chatbot Performance in Analyzing Clinical Scenarios versus Medical Residents: A Novel Approach in Chest Diseases Education<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: ChatGPT and Gemini have significant potential as clinical decision-support systems and educational assistants. However, rather than replacing human factors in clinical reasoning and emergency management, they should be positioned as complementary tools that accelerate physicians' access to theoretical knowledge.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Mehmet Hakan Bilgin<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 14, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41973771\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Recurrent episodes of pneumonia are associated with worse lung function in people with HIV<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: In PWH with a high prevalence of inhalational substance use, recurrent episodes of pneumonia are associated with a commensurate decline in lung function in PWH characterized by airflow obstruction and diffusion limitations. While further studies are needed to elucidate the underlying mechanism, this work highlights the importance of preventing recurrent pneumonia in PWH in order to preserve lung function.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Sven J Walderich<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 13, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41970202\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Incidence of acute exacerbation and its related factors among chronic obstructive pulmonary disease patients aged 40 years and older in China<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: AECOPD incidence and hospitalization rates remain substantial among community-dwelling COPD patients aged \u226540 years in China, with a significantly higher burden in southern region. Early-life severe respiratory disease, greater symptom severity, poorer lung function, and multiple comorbidities are strongly associated with increased AECOPD risk. Addressing regional disparities, strengthening comprehensive assessment and management, identifying high-risk individuals, and implementing...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Qi Luo<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 13, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41958178\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Accelerating PREFUL MRI: Comparison of Registration Methods and Impact of Time Series Reduction<\/a><\/div>\n<div class=\"hungryfeed_item_description\">The purpose of this study is to evaluate whether accelerated registration and reduced acquisition times preserve the robustness of phase-resolved functional lung (PREFUL) MRI, thereby improving clinical feasibility by facilitating integration into tight time slots and enabling faster turnaround of results. PREFUL MRI at 1.5 T was retrospectively analyzed in 28 patients with chronic obstructive pulmonary disease (COPD) and 56 healthy volunteers. Image registration was performed using Advanced...<\/div>\n<div class=\"hungryfeed_item_author\">Author: A Voskrebenzev<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 10, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41958623\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>A Prospective Analysis of Cognitive Functions in Stable Nonhypoxemic Chronic Obstructive Pulmonary Disease Patients at a Tertiary Care Center, Jaipur<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: Patients with COPD have a higher risk of CI compared to the age-matched healthy volunteer group.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Pratima Agrawal<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 10, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41961412\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Feasibility of quantitative pulmonary function imaging in real-world cardiovascular magnetic resonance<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Providing insights into the feasibility of pulmonary function assessment in real-world cardiovascular magnetic resonance (CMR) practice by applying Phase-REsolved FUnctional Lung imaging (PREFUL). We retrospectively analyzed consecutive patients who underwent PREFUL imaging in addition to routine 1.5T CMR between September 2023 and January 2024. PREFUL was acquired in three coronal slices, with a prototype tool used to derive quantitative perfusion and ventilation defect percentages (QDP and...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Jan Gr\u00f6schel<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 10, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41957616\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Thoracic myosteatosis and adipose tissue in COPD: associations of muscle quality and CT biomarkers with GOLD classification<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSION: Thoracic CT-derived body composition markers are strongly associated with pulmonary function in individuals with COPD. Muscle quality and fat distribution serve as important indicators of disease severity and may enhance clinical evaluation and risk stratification beyond conventional indices such as body mass index. Incorporating CT-based biomarkers into routine assessment may facilitate more personalized disease monitoring and management strategies.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Murathan Koksal<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 9, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41957652\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Diet-induced obesity alleviates epithelial damage in hyperoxic acute lung injury (HALI) in mice<\/a><\/div>\n<div class=\"hungryfeed_item_description\">CONCLUSIONS: Diet-induced obesity did not influence functional measures in the acute phase of hyperoxia but prevented depletion of body fat reserves and mitigated structural lung damage indicating a beneficial impact on regeneration. This supports a biological basis for an obesity paradox in ARDS, and should be taken into account for future individualized prevention and therapy in obese patients.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Morten Kampelmann<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 9, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41951869\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Cystic fibrosis care today-a narrative review based on views of experts, patients and the public<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Cystic fibrosis (CF) is one of the most common rare, genetic diseases. Newly available, highly effective modulator therapy (HEMT) improves many domains of CF pathophysiology. Thereby, HEMT challenges current standards of care and prediction models of disease outcomes.We established a public patient involvement (PPI) group including experts and caregivers of children with CF and collated a narrative review on CF management. This review is based on the views of healthcare professionals and...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Florian Singer<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 8, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41939729\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>&lt;em&gt;Coccidioides&lt;\/em&gt; skin test performance and patterns of prior immunity to coccidioidomycosis among a large population of males entering California state prisons, 2015-2024: a population-based modelling study<\/a><\/div>\n<div class=\"hungryfeed_item_description\">BACKGROUND: The incidence of coccidioidomycosis-an emerging fungal infection-is high within California state prisons. In 2015, California began offering a Coccidioides skin test, Spherusol\u00ae, to adult males upon entry into prison, with those susceptible to coccidioidomycosis restricted from placement in two prisons with highest incidence. This study aimed to understand test performance within the incarcerated population and to estimate population-level immunity and force of infection (FOI) by age...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Jennifer R Head<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 6, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41940030\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Airway mucus in infection<\/a><\/div>\n<div class=\"hungryfeed_item_description\">The mucosa of the airways is under a near-constant barrage of contaminants, allergens, and pathogens that can accumulate and cause irritation or infection if not promptly removed. Mucus, composed of a mucin glycoprotein mesh, protects the airways from these contaminants by entrapment and removal. Several diseases stall the protection provided by the mucus by altering its components and biophysical properties. This review provides an overview of how the defensive mucus of the airways functions in...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Caitlin Costello<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 6, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41933608\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Admission Eosinophil Count Is Associated With Hospital Resource Use in Community-Acquired Pneumonia: A Prospective Multicenter Study<\/a><\/div>\n<div class=\"hungryfeed_item_description\">BACKGROUND: Eosinopenia has been associated with adverse outcomes in community-acquired pneumonia (CAP). However, its relationship with hospital resource use remains unclear.<\/div>\n<div class=\"hungryfeed_item_author\">Author: Barbara Christine Weckler<\/div>\n<div class=\"hungryfeed_item_date\">Posted: April 4, 2026, 10:00 am<\/div>\n<\/div>\n<div class=\"hungryfeed_item\">\n<div class=\"hungryfeed_item_title\"><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32644707\/?utm_source=SimplePie&amp;utm_medium=rss&amp;utm_campaign=None&amp;utm_content=1n3mGKHZyalujwPkqwUbwAn07fCGhPg2z0aIa7FCdEf3MAIk3p&amp;fc=None&amp;ff=20260522114647&amp;v=2.20.0\" target='_blank'>Chronic Obstructive Pulmonary Disease (COPD)<\/a><\/div>\n<div class=\"hungryfeed_item_description\">Chronic obstructive pulmonary disease (COPD) is a common, preventable, and treatable disease characterized by persistent and progressive airflow limitation caused by airway or alveolar abnormalities, typically arising from significant exposure to noxious particles or gases. The airflow limitation results from a combination of small airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), with the relative contribution of each varying between individuals.[GOLD. 2024...<\/div>\n<div class=\"hungryfeed_item_author\">Author: Venkatkiran Kanchustambham<\/div>\n<div class=\"hungryfeed_item_date\">Posted: January 1, 2026, 11:00 am<\/div>\n<\/div>\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":71,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.library.wmuh.nhs.uk\/wp\/wp-json\/wp\/v2\/pages\/201"}],"collection":[{"href":"https:\/\/www.library.wmuh.nhs.uk\/wp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.library.wmuh.nhs.uk\/wp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.library.wmuh.nhs.uk\/wp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.library.wmuh.nhs.uk\/wp\/wp-json\/wp\/v2\/comments?post=201"}],"version-history":[{"count":3,"href":"https:\/\/www.library.wmuh.nhs.uk\/wp\/wp-json\/wp\/v2\/pages\/201\/revisions"}],"predecessor-version":[{"id":3572,"href":"https:\/\/www.library.wmuh.nhs.uk\/wp\/wp-json\/wp\/v2\/pages\/201\/revisions\/3572"}],"up":[{"embeddable":true,"href":"https:\/\/www.library.wmuh.nhs.uk\/wp\/wp-json\/wp\/v2\/pages\/71"}],"wp:attachment":[{"href":"https:\/\/www.library.wmuh.nhs.uk\/wp\/wp-json\/wp\/v2\/media?parent=201"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}