New England Journal of Medicine – Pediatrics News

Presentation of Case. Dr. Batul Kaj: A 14-month-old boy was evaluated in the pediatric gastroenterology clinic of this hospital because of vomiting. The patient was born at another hospital to a 35-year-old mother by cesarean section because of arrest of the second stage of labor after an…
Posted: September 19, 2019, 12:00 am
To the Editor: Much has been written on the potential dangers of sporting activities in children and young adults with potentially arrhythmogenic cardiac conditions. Current international guidelines recommend avoidance of strenuous activity and competitive sports in persons with these conditions.…
Posted: September 19, 2019, 12:00 am
To the Editor: The rapid increase in adolescents’ use of electronic cigarettes (known as vaping) during the past decade has aroused public health concern, recently heightened by potential links between vaping and acute lung injury. Adolescents who vape use a device such as an e-cigarette to inhale…
Posted: September 18, 2019, 12:00 am
Presentation of Case. Dr. Bethany L. Bartley (Pediatrics): A 22-year-old woman was seen in the pediatric pulmonary clinic of this hospital because of chest pain, cough, and dyspnea on exertion. The patient had been well until she was 2 months of age, when an episode of bronchiolitis occurred. After…
Posted: September 12, 2019, 12:00 am
Those with even a rudimentary knowledge of biomedical progress understand how advances in delineating the components of the immune system have led to new means of manipulating it, including vaccines as well as drugs and biologic agents to ameliorate cancer and autoimmune conditions. The importance…
Posted: September 12, 2019, 12:00 am
On August 3, 2019, a white supremacist with an AK-47 opened fire on shoppers in an El Paso Walmart, killing 22 people, including a 15-year-old, and wounding scores more, including a 9-year-old and a 2-year-old. Parents and grandparents died protecting their children and grandchildren. That Latinos…
Posted: September 11, 2019, 12:00 am
Presentation of Case. Dr. Hung M. Le (Pediatrics): A 16-year-old girl was seen in the sports concussion clinic at this hospital because of headache, dizziness, balance problems, fatigue, irritability, and difficulties with sleep and concentration after she had head trauma during a sailboat race.…
Posted: August 29, 2019, 12:00 am
The treatment of children has been pivotal in the development of laws ensuring that medications are tested for safety and efficacy before widespread use. The first law imposing federal regulations of biologic products was the Biologics Control Act of 1902, which was enacted in response to the…
Posted: August 29, 2019, 12:00 am
Figure 1.
Posted: August 29, 2019, 12:00 am
Type 1 diabetes mellitus, a chronic autoimmune disease that usually begins in childhood, affects more than 1.25 million Americans, and its worldwide prevalence is increasing. Although insulin was discovered almost a century ago and the technologies for administering and monitoring insulin treatment…
Posted: August 15, 2019, 12:00 am
The incidence of type 2 diabetes in children and adolescents is increasing, with the increase driven by childhood obesity, and type 2 diabetes disproportionately affects disadvantaged minorities. Metformin is the regulatory-approved treatment of choice for most youth with type 2 diabetes early in…
Posted: August 15, 2019, 12:00 am
Type 1 diabetes is caused by the autoimmune destruction of insulin-producing beta cells in the islets of Langerhans, which leads to dependence on exogenous insulin for survival. Approximately 1 million to 1.5 million Americans have type 1 diabetes, which is one of the most common diseases of…
Posted: August 15, 2019, 12:00 am
Sickle cell disease affects approximately 100,000 persons in the United States and reduces life expectancy by approximately 30 years. The disease is caused by a single amino acid substitution resulting in the production of sickle hemoglobin (HbS). HbS polymerizes when deoxygenated, resulting in…
Posted: August 8, 2019, 12:00 am
Boy Erased and The Miseducation of Cameron Post, two movies released in 2018, raised awareness of efforts to change people’s sexual orientation, also known as conversion therapy. These films portray the trauma inflicted by such efforts and the patently false science underpinning this debunked…
Posted: August 8, 2019, 12:00 am
Affecting an estimated 100,000 Americans and millions worldwide, sickle cell disease is among the most common inherited blood disorders in humans and is associated with profound complications and premature death. The pathophysiology of sickle cell disease begins with a single amino acid…
Posted: August 8, 2019, 12:00 am
You can’t walk into a pediatric intensive care unit (PICU) anywhere in the world without being viscerally struck by sights, smells, and sounds that can easily overwhelm the uninitiated. Every child in a PICU is attached to various monitors that seem to reduce that child’s life to a set of vital…
Posted: August 8, 2019, 12:00 am
Severe anemia (hemoglobin level, If standard formulae for transfusion volume are applied, the one-size-fits-all recommendation of 20 ml per kilogram appears to underestimate transfusion requirements by approximately 30%. A consensus guideline on transfusion in critically ill children noted a weak…
Posted: August 1, 2019, 12:00 am
Yellow fever is a mosquito-borne viral disease endemic to tropical and subtropical regions in Africa and the Americas. Infection with yellow fever virus can result in subclinical to severe illness, characterized by fever, jaundice, and hemorrhage. There were an estimated 51,000 to 380,000 severe…
Posted: August 1, 2019, 12:00 am
Severe anemia (hemoglobin level In the Transfusion and Treatment of Severe Anemia in African Children Trial (TRACT), we compared four interventions. Here, we compare immediate transfusion with no immediate transfusion, in which transfusion was triggered by the development of new signs of clinical…
Posted: August 1, 2019, 12:00 am
Figure 1.
Posted: August 1, 2019, 12:00 am
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